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Atlas of 6.3 Million Brain Cells Maps Gene Shifts Across Lifespan and Disorders
x/demis-roussos
— Sep 23, 2026
An atlas of 6.3 million prefrontal cortex cells from 1,494 donors up to age 108 maps gene-activity shifts across the lifespan and in Alzheimer’s, schizophrenia and other disorders.
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Dana Whitfield
With cells from nearly 1500 donors it should reveal patterns in Alzheimer's that smaller studies have missed.
LB Pharmaceuticals accelerates Phase 3 NOVA-2 timeline across 25 U.S. sites, targets 1H 2027 topline
x/united-states-of-america
— Jul 22, 2026
LB Pharmaceuticals now expects topline results from the Phase 3 NOVA-2 trial of LB-102 in schizophrenia in the first half of 2027, ahead of prior guidance, with a planned pre-NDA FDA meeting in the second half of 2027. The company highlights faster enrollment across about 460 patients at 25 U.S. sites, possible open-label extension and ongoing Phase 2 studies in bipolar depression and major depressive disorder, plus a cash runway into 2029 to support multiple readouts.
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Dominguez convicted of involuntary manslaughter in Davis
World
— Jul 21, 2026
A Yolo County jury in Davis found Carlos Reales Dominguez guilty of involuntary manslaughter for two killings and acquitted him of second-degree murder and attempted murder, with the case moving to a sanity phase to determine criminal responsibility given his schizophrenia. The retrial followed a 2025 mistrial and longstanding debate over whether cannabis-induced psychosis negated intent, with prosecutors positioning deliberate actions despite mental illness and the defense arguing insanity at the time of the attacks.
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Top Psychiatrist Argues Schizophrenic Patients Can Consent To Sex Change Surgeries
Reporting
— Jun 5, 2024
This is the second article in the “WPATH Tapes” series on the World Professional Association for Transgender Health and the gender medical industry. Read the overview of our investigation here . A leader of the world’s…
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IJR
EPA Shelves Biden’s Chemical Spill Rule Until 2030 And Strips Its Climate Mandates
Simon August · 6 min · 4h