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Trontinemab Dementia-Prevention Trial Spans 18 Countries
Health
— Sep 25, 2026
Alzheimer’s research is advancing on several fronts, including trials of trontinemab to potentially prevent disease in people without symptoms, experimental tau-targeting therapies, and early research into the naturally occurring peptide catestatin. While approved amyloid-targeting drugs and other candidates offer hope of slowing decline, their effectiveness, safety, and cost remain important concerns.
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TSMC Posts Record Q3 Revenue, Beats Forecasts
Tech
— 10h
TSMC posted record third-quarter revenue of about NT$1.49 trillion, up roughly 50% from a year earlier and above analyst forecasts. The surge, fueled by strong demand for AI chips, underscores the momentum in the global AI buildout; investors await the company’s earnings report and updated outlook.
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Watford host winless Burnley as West Brom meets Birmingham in derby
x/james-morrison
— 4h
Championship action this weekend features Swansea aiming to protect their strong start against Norwich, whose defense has struggled, while in-form Stoke visit Bolton and West Brom host Birmingham in a local derby. At the other end of the table, struggling Derby seek a turnaround against Wrexham; Charlton and Bristol City meet as Bristol City look to build on improved form.
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Strong earthquake jolts Davao Occidental, Mindanao
x/davao-occidental
— 2d
A shallow earthquake struck Mindanao on Thursday, with estimates ranging from magnitude 5.7 to 6.4; Phivolcs said significant damage was not expected but warned that aftershocks were possible. Shaking was reported across parts of the region, and officials urged residents to remain alert.
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IJR
Was NIH’s Trans Kids Research Russ Vought’s Last Straw?
Emily Kopp · 8 min · 1h
Browns Rookie Denzel Boston Leads NFL in Yards Per Catch
x/denzel-boston
— 2d
Cleveland Browns rookie wide receiver Denzel Boston has made an immediate impact, leading rookies with 284 receiving yards and two touchdowns through four games while averaging 21.8 yards per catch. His big-play connection with quarterback Deshaun Watson has helped fuel the Browns’ strong start and made Boston one of the NFL’s most productive early-season rookies.
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Most Influential Women in World History
Yourlist
— Ranking
From ancient queens who ruled empires to modern activists who changed laws, these women left indelible marks on politics, science, and culture. Vote for who you think shaped history most profoundly.
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Former Oregon Safeties Deliver Across NFL
Sports
— 2d
Arizona rookie Jayden Williams is preparing to take over at left tackle after Paris Johnson Jr.’s season-ending injury. Elsewhere, Green Bay safety Evan Williams had a standout Week 4, while fantasy analysts expect Dallas running back Javonte Williams to be a strong touchdown option against Tampa Bay.
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Savannah Port Sets September Container Record
Business
— 1d
The Port of Savannah handled a record 504,015 containers in September, up 3.7% from a year earlier, as strong imports and cargo delayed by typhoons in Asia extended the peak shipping season. The Georgia Ports Authority said first-quarter volumes also rose 2.7%, while major terminal upgrades are underway to expand capacity.
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NFL Teams Reach Varied Starts After Four Weeks
Sports
— 2d
After four NFL weeks, several teams are clustered at .500, making Sunday’s Steelers-Colts matchup an important test for both; the 3-1 Seahawks have impressed behind Jaxon Smith-Njigba and a strong defense, while the 2-2 Panthers are encouraged by Bryce Young’s improved play. Denver is also 2-2, with its pass rush and offensive line standing out but Bo Nix drawing concern, while the wider league roundup highlights New England’s upset win over Buffalo and Drake Maye’s performance.
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Barclays Upgrades Estée Lauder, Raises Target to $108
Finance
— 3d
Barclays upgraded Estée Lauder to Overweight and raised its price target to $108 from $97, citing stronger, more geographically balanced sales and expectations that operating changes will improve margins while supporting reinvestment. The stock rose 2.2% in premarket trading after the upgrade.
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FaithTap
Corrie ten Boom's Sister Betsie Prays for the Guards
Prisoner intercedes for her Ravensbrück tormentors
2m
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Pelicans Rally From 24-Point Deficit, Beat Thunder
x/jeremiah-fears
— 2d
The Pelicans rallied from a 24-point deficit to beat the Thunder 116-110 in their preseason opener, powered by an 18-0 third-quarter run and a strong showing from the reserve unit led by Bennedict Mathurin. The comeback offered promise from New Orleans’ bench, but its starters and defense struggled against an Oklahoma City team resting several key players.
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“Be strong and courageous. Do not be afraid or terrified because of them, for the Lord your God goes with you; he will never leave you nor forsake you.”” — Deuteronomy 31:6, New International Version
x/new-international-version
— 9h
Posted to IJR by IJR.
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New York Pizza vs Chicago Deep Dish
Yourlist
— VS Battle
The foldable slice versus the fork-and-knife casserole — America's longest-running food fight.
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Fourteen Receivers Join Biletnikoff Award Watch List
Sports
— 21h
Missouri’s Cayden Lee, Syracuse’s Umari Hatcher, Colorado’s Joseph Williams and Arkansas’ Chris Marshall were added to the Biletnikoff Award watch list for college football’s top receiver. Their strong starts include Hatcher’s five touchdowns, Williams’ 454 yards and five scores, and Marshall’s 549 yards, while Lee has also delivered multiple standout performances.
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Wave-Shaped Designs Cut Building Wind Pressures Up to 60%
Science
— 1d
Florida State University researchers found that wave-shaped walls and roofs on low-rise buildings can reduce peak hurricane-wind pressures near vulnerable corners by 40% to 60% in wind-tunnel tests. The design could offer engineers a way to improve wind resilience through building shape, alongside conventional measures such as stronger materials and rounded corners.
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Two universities report seven sexual assault allegations
Health
— 3d
The University of Oregon reported five sexual assault incidents during the first week of classes, prompting Oregon lawmakers to urge stronger campus responses and survivor support; officials say the cases are not believed to be related and are under investigation. At the University of Texas at Arlington, police notified students about two alleged assaults in a dorm weeks after they reportedly occurred, saying there is no known ongoing threat and the investigation continues.
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IJR
Cartel Lieutenant’s Capture Could Provide New Links to Former Mexican President’s Son
Ildefonso Ortiz and Brandon Darby · 4 min · 1h
Dodgers Move Ohtani to Fifth for Game 3
x/shohei-ohtani
— 3d
With the NLDS tied 1-1 and Chris Sale set to start for Atlanta, Dodgers manager Dave Roberts is weighing lineup changes, including moving Shohei Ohtani lower and adding right-handed hitters. Roberts also said Edwin Díaz has reentered consideration to close after a strong outing; Atlanta had rested Sale for Game 2 to line him up for the matchup.
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Can you actually read a map?
Quizie
— Quiz
Fifteen world-geography questions. Most people miss at least three — the AI grades you and names your traveler rank.
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Vikings Reach 4-0 With Two Touchdownless Wins
x/will-reichard
— 3d
The 4-0 Minnesota Vikings made NFL history by winning twice without scoring a touchdown, most recently beating the Dolphins 15-10 on five Will Reichard field goals. Their start has been powered by a league-leading defense and strong special teams, while the offense has struggled to produce.
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Hornets Nearing $200M Brandon Miller Extension
x/brandon-miller
— 3d
The Charlotte Hornets are reportedly making progress toward a long-term extension with Brandon Miller, with projections putting the deal above $200 million. Miller is considered among the strongest candidates to sign before the deadline; if no deal is reached, he would become a restricted free agent, allowing Charlotte to match other teams’ offers.
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SEC Teams Face Offensive, Defensive Tests
Sports
— 2d
SEC football teams face distinct tests: South Carolina’s offense has leaned heavily on quarterback LaNorris Sellers and needs greater passing accuracy and more dependable depth, while Alabama’s third-down defense will be pivotal against Georgia’s highly efficient offense. Kentucky, meanwhile, has paired a strong offensive line with an aggressive pass rush to fuel its 4-1 start.
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Gasser, Buehler Set for NLDS Game 4
x/walker-buehler
— 19h
The Brewers will start left-hander Robert Gasser in Game 4 of the NLDS against the Padres, hoping to keep their season alive after a record-tying 12th straight road playoff loss. Gasser was strong late in the regular season, but Milwaukee may rely heavily on its bullpen.
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Daily Caller News Foundation
Was NIH’s Trans Kids Research Russ Vought’s Last Straw?
About a month before the White House considered an executive order giving it greater control over the National Institutes of Health, outside experts close to the administration learned of an NIH-backed project advocating sex-change procedures in children, according to a former administration official. Reversing the tide of transgender surgeries in minors, including securing the closure of five top
1h · 2 reads
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Wisconsin Line 5 Reroute Breaches Aquifer Near Marengo
Environment
— 5d
Construction on Enbridge’s Line 5 reroute breached an aquifer near Wisconsin’s Marengo River, prompting state monitoring as the company says it is containing the water flow and assessing next steps. Tribal and environmental advocates criticized the work and urged stronger oversight, while the Great Lakes Indian Fish and Wildlife Commission has raised concerns about water loss and potential impacts.
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Raleigh Detective Fired After Six Criminal Charges
World
— 1d
Raleigh police fired detective Christopher Andre Reed after his arrest in an off-duty incident at a Wake Forest restaurant, where authorities allege he tried to hit patrons and assaulted the manager. Police say he later resisted officers and assaulted an emergency medical technician; he faces six charges, including assault-related offenses and disorderly conduct.
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Monangai Leads Bears Past Jets 23-12
x/minkah-fitzpatrick
— Sep 29, 2026
The 1-2 Jets head to Chicago looking to rebound after consecutive close losses, with Geno Smith’s strong passing providing a bright spot but the running game and offensive line needing improvement. New York also hopes to end a 20-game interception drought, while Breece Hall’s quad injury could leave the backfield to Braelon Allen and Isaiah Davis.
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Deer Season Opens in Pennsylvania, Minnesota Licensing Changes
Environment
— 5d
Minnesota’s new mostly digital licensing system has prompted the DNR to urge deer hunters to buy licenses early, with harvests also requiring electronic validation instead of physical tags. Pennsylvania’s archery season now includes Sunday hunting and updated rules for disposing of potentially disease-carrying deer parts, while proposals to let Pennsylvania hunters choose the firearms opener and restore baiting in Michigan’s Lower Peninsula face uncertain prospects.
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Genomics Programs Plan Broader Screening Across Healthcare
Health
— 2d
Researchers are testing whether genome sequencing can broaden screening for treatable hereditary conditions: Yale is piloting testing through primary care, while an Oregon study aims to assess screening newborns for hundreds of conditions. A national survey of French perinatal health professionals found strongest support for conditions with effective early interventions, while highlighting that sequencing’s ability to reveal many kinds of findings complicates traditional screening criteria.
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IJR
Flock Deal Pulls Back Curtain On 20 Small-Town Cameras Wired Into Nationwide Network
Dylan Kresak · 4 min · 3h
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